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Full Prescribing Information
Important Safety Information
Patient Site
Stay Informed
Explore Our Medical Resources
Request A Rep

BAXFENDY is an aldosterone synthase inhibitor indicated, in combination with other antihypertensive drugs, for the treatment of hypertension... BAXFENDY is an aldosterone synthase inhibitor indicated, in combination with other antihypertensive drugs, for the treatment of hypertension to lower blood pressure in adults who are not... BAXFENDY is an aldosterone synthase inhibitor indicated, in combination with other antihypertensive drugs, for the treatment of hypertension to lower blood pressure in adults who are not adequately controlled on other agents. Lowering blood pressure reduces the risk of fatal and nonfatal cardiovascular events, primarily strokes and myocardial infarctions.

RESOURCES

PRESCRIBING INFORMATION / RESOURCES

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PATIENT RESOURCES

ASPN PATIENT GUIDE

ASPN PATIENT GUIDE

Helps your patients understand what to expect when you prescribe BAXFENDY to ASPN Pharmacies.

Download

BAXFENDY Savings Card

BAXFENDY Savings Card

Eligible commercially insured patients pay as little as $15 per 30-day supply with the BAXFENDY Savings Card.

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BAXFENDY Patient Brochure

BAXFENDY Patient Brochure

Educates patients about the risks of uncontrolled hypertension, the blood pressure hormone aldosterone, and how BAXFENDY may help.

Download English

Download Spanish

Prior Authorization Support

Overviews the suite of services available to support offices prescribing BAXFENDY.

Download

BAXFENDY StartSmart

BAXFENDY StartSmart

An interactive educational tool designed to provide your patients with the most important information about starting BAXFENDY.

Visit Now

BAXFENDY Letter of Medical Necessity

Letter of Medical Necessity

Templated resource for use by healthcare providers when responding to an insurance company request for a Letter of Medical Necessity in support of prescribing BAXFENDY.

Download

BAXFENDY Sample Appeal Letter

Sample Appeal Letter

Template can be used by a healthcare provider to appeal a denial of access to BAXFENDY.

Download

Mail-in Rebate Form

Mail-in Rebate

Downloadable form to help receive reimbursement on valid prescription claims.

Download

Prescribing to ASPN Pharmacies

Prescribing to ASPN Pharmacies

A quick reference guide for prescribing to ASPN Pharmacies.

Download

ASPN PATIENT GUIDE

ASPN PATIENT GUIDE

Helps your patients understand what to expect when you prescribe BAXFENDY to ASPN Pharmacies.

Download

BAXFENDY Savings Card

BAXFENDY Savings Card

Eligible commercially insured patients pay as little as $15 per 30-day supply with the BAXFENDY Savings Card.

Download

BAXFENDY Patient Brochure

BAXFENDY Patient Brochure

Educates patients about the risks of uncontrolled hypertension, the blood pressure hormone aldosterone, and how BAXFENDY may help.

Download English

Download Spanish

Prior Authorization Support

Overviews the suite of services available to support offices prescribing BAXFENDY.

Download

BAXFENDY StartSmart

BAXFENDY StartSmart

An interactive educational tool designed to provide your patients with the most important information about starting BAXFENDY.

Visit Now

BAXFENDY Letter of Medical Necessity

Letter of Medical Necessity

Templated resource for use by healthcare providers when responding to an insurance company request for a Letter of Medical Necessity in support of prescribing BAXFENDY.

Download

BAXFENDY Sample Appeal Letter

Sample Appeal Letter

Template can be used by a healthcare provider to appeal a denial of access to BAXFENDY.

Download

Mail-in Rebate Form

Mail-in Rebate

Downloadable form to help receive reimbursement on valid prescription claims.

Download

Prescribing to ASPN Pharmacies

Prescribing to ASPN Pharmacies

A quick reference guide for prescribing to ASPN Pharmacies.

Download

ASPN PATIENT GUIDE

Helps your patients understand what to expect when you prescribe BAXFENDY to ASPN Pharmacies.

Download

BAXFENDY Savings Card

BAXFENDY Savings Card

Eligible commercially insured patients pay as little as $15 per 30-day supply with the BAXFENDY Savings Card.

Download

BAXFENDY Patient Brochure

BAXFENDY Patient Brochure

Educates patients about the risks of uncontrolled hypertension, the blood pressure hormone aldosterone, and how BAXFENDY may help.

Download English

Download Spanish

Prior Authorization Support

Overviews the suite of services available to support offices prescribing BAXFENDY.

Download

BAXFENDY StartSmart

BAXFENDY StartSmart

An interactive educational tool designed to provide your patients with the most important information about starting BAXFENDY.

Visit Now

BAXFENDY Letter of Medical Necessity

Letter of Medical Necessity

Templated resource for use by healthcare providers when responding to an insurance company request for a Letter of Medical Necessity in support of prescribing BAXFENDY.

Download

BAXFENDY Sample Appeal Letter

Sample Appeal Letter

Template can be used by a healthcare provider to appeal a denial of access to BAXFENDY.

Download

Mail-in Rebate Form

Mail-in Rebate

Downloadable form to help receive reimbursement on valid prescription claims.

Download

Prescribing to ASPN Pharmacies

A quick reference guide for prescribing to ASPN Pharmacies.

Download

Stay informed about BAXFENDY

IMPORTANT SAFETY INFORMATION for BAXFENDY® (baxdrostat)

IMPORTANT SAFETY INFORMATION for BAXFENDY® (baxdrostat)

Warnings and Precautions

Hyperkalemia

BAXFENDY can cause hyperkalemia. Assess serum potassium prior to initiation of BAXFENDY and monitor periodically during treatment. Correct serum potassium abnormalities prior to initiation. More frequent monitoring is recommended for patients at increased risk of hyperkalemia (eg, patients ≥65 years of age, those with diabetes mellitus or chronic kidney disease, and those receiving concomitant medications that increase serum potassium). If hyperkalemia occurs, treat hyperkalemia and consider interrupting or discontinuing BAXFENDY. Consider more frequent monitoring in patients who restart BAXFENDY after experiencing hyperkalemia. Permanently discontinue if clinically significant hyperkalemia recurs.

Hyponatremia

BAXFENDY can cause hyponatremia. Assess serum sodium prior to initiation and monitor periodically during treatment. Correct serum sodium abnormalities prior to initiation. More frequent monitoring is recommended for patients with low baseline serum sodium concentrations and those at risk for hyponatremia. If clinically significant hyponatremia occurs, treat the hyponatremia and consider interrupting or discontinuing BAXFENDY. Consider more frequent monitoring of serum sodium in patients who restart BAXFENDY after experiencing hyponatremia. Permanently discontinue if clinically significant hyponatremia recurs.

Adverse Reactions

Most frequently reported adverse reactions (≥2% with BAXFENDY and greater (≥1%) than placebo in pooled, placebo-controlled trials) reported for BAXFENDY 1 mg and 2 mg, respectively, were hyperkalemia (6.6%, 10.2%), hypotension (2.1%, 3.6%), hyponatremia (2.1%, 3.2%), dizziness (3.0%, 2.9%), and muscle spasms (1.8%, 2.9%).

Drug Interactions

Drugs That Increase Serum Potassium: Monitor serum potassium more frequently when BAXFENDY is used concomitantly with drugs that impair potassium secretion or increase serum potassium. Concomitant use may increase the risk of hyperkalemia.

Strong and moderate CYP3A inducers: Monitor the therapeutic effect of BAXFENDY more frequently during concomitant use. BAXFENDY is a CYP3A substrate.

INDICATION for BAXFENDY

BAXFENDY is an aldosterone synthase inhibitor indicated, in combination with other antihypertensive drugs, for the treatment of hypertension to lower blood pressure in adults who are not adequately controlled on other agents. Lowering blood pressure reduces the risk of fatal and nonfatal cardiovascular events, primarily strokes and myocardial infarctions.

DOSING

The recommended dosage of BAXFENDY is 2 mg orally once daily. For patients at increased risk of hyperkalemia or hyponatremia, the recommended dosage is 1 mg orally once daily.

Please see accompanying US Full Prescribing Information for BAXFENDY.

You may report side effects related to AstraZeneca products .

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